Finding Sequence: A Human Genome Project Resource


The Human Genome Project, or HGP, can best be looked at as an international scientific project. Its main goal is to conduct research in the hopes of finding out the sequence of pairs of chemical bases. Its equally important main goal is also to point out and then map up to 25,000 genes from the human genome from a functional as well as physical viewpoint. Initially, the Project’s goal was to map the nucleotides that were found in a human haploid reference genome.

What is the Human Genome Project?

The Human Genome Project began in 1990 as a way of mapping human genes. It was recognized that mapping human genes was vital, due to the need to develop medicines and other factors of health care. The aim of this Project is to better understand the human species’ genetic makeup. Nonetheless, this Project has still been able to include research on some nonhuman organisms like the lab mouse, the fruit fly, and even the E. coli bacterium. To date, the Project is recognized as one of the biggest investigative projects in all the annals of science.

? Human Genome Project Explained: Web Page that explains all visitors could want to know about the Project.

? Introduction to the Human Genome Project: Website that an overview of the Project.

? Explanation of the Human Genome Project: Website that provides a thorough explanation of the Project.

? Importance of Human Genome Project: Web Page that details the importance of the Project.

? Human Genome Project Essay: Walk through of the Human Genome Project.

Discoveries of the Human Genome Project

The discoveries of the Project include information that has impacted the scientific world. The Project has discovered that human beings possess about 20,500 genes, which is double that of roundworms and the same as mice. It also found out that about 1.1 percent to 1.4 percent of the Project’s genome sequence codes are for proteins. The third discovery of the Project was that the human genome features more segmental duplications than other genomes of mammals. Finally, the last discovery of the Project was that fewer than 7 percent of protein families seemed to be vertebrate specific.

? Discoveries of the Human Genome Project: Web Page that details some of the discoveries of the Project.

? Why the Human Genome Project?: Web Page that talks about how the motivation for discoveries have driven the Project’s research.

? Decade of Discovery: Article that explains the 10 years of discovery that have resulted thanks to the Project.

? Human Genome Project and Drug Industry: Article that explains the discoveries in drug development from the Project’s research.

? Gene Discovery: Write-up that discusses how the development of gene discovery has increased thanks to the Project.

Ethical, Legal, and Social Implications

5 percent of the budget for the Project was reserved to address the ethical, legal and social implications of a greater availability of genetic information. The biggest disparagement that ethical, legal and social implications with regards to the Project have faced is that they fail to address population-based research. The research done by the Project is classified as genetic variation research. However, the majority of the ethical guidelines regarding the Project only focus on the principle of individual rights as opposed to group rights.

? Ethical Resource Page: Web Page that features dozens of link to other websites that debate the ethics surrounding the Project.

? Human Genetics Commission Website: Website that body that looks at how news from human genetics will impact persons.

? Genes and Choices: Website of publications that talk about the ethical implications of genome research.

? Genetic Discrimination: Information on the bill President Clinton signed in February of 2000, which prohibited genetic discrimination.

? Report on Safe Genetic Testing: Web Page that details the efforts to make genetic testing safe.

Medical and Scientific Applications

Even though the interpretation of the data obtained through the Project’s research is still in its infancy, scientists can infer that medical and scientific applications will become increasingly possible. New advances in both biotechnology and medicine are expected consequences of the knowledge revealed through the Project. Even before the Project had completed its work, some medical companies were already able to benefit from the discoveries in the research by offering genetic tests that can predict the predisposition of people to certain kinds of sicknesses. Biological scientists are now able to use the information from the Project in order to narrow down to a certain gene in investigation into a certain type of cancer.

? Guide to the Human Genome Project: Web Page that offers links to more information on the applications derived from the Project.

? Human Genome Project Applications: Information on the applications of what has been found so far in the Project.

? Future Benefits: Write-up that discusses the future applications of the Project’s works.

? Applications of the Human Genome Project: Essay that talks about the applications of the Project.

? Brief Discussion of Applications: Web Page that includes a mention of the possible applications of the Project’s research.

The Next Step in Genomics

The next step in genomics is to use the information that the successful genome sequencing of certain items will provide. For instance, the genetic code of rice was sequenced a few years ago, and this has profitable implications for both consumers and farmers, largely from all the research focused on the crop. Other future goals include sequencing the code of crops like Cassava, which is a crop that feeds about 600 million people, mostly in third world countries. Do-gooder scientists and activists assert that sequencing the code of crops like Cassava will maximize its potential, which would make it more beneficial to poor people in third world countries.

? Food Source Article: Article that deals with the next step in genomics applications.

? Next Steps in Research: Informative web page from the government that talks about what’s next in genomics.

? Pharmacogenomics: Web Page that features a video relating to the next step in pharmacogenomics developments.

? Genomics Research Grant: Article talking about how a grant paves the way for further genome research.

? Common Diseases: News release about more funding for research on the biological roots of disease.